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Chai Discovery

Design Engineer

San Francisco office
Level
Mid
Work type
On-site · San Francisco

Not stated in the posting: salary, visa.

Open. First seen 2 October 2026.

About the role

Chai Discovery's standard text

About Chai Discovery

Chai Discovery builds the computer-aided design suite for molecules. Eli Lilly, GSK, Pfizer, Bristol Meyers, argenx and Novartis all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.

We train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.

We value diverse perspectives and are ready to find greatness in unexpected places.

About the role

Define and build the workspace that scientists use to develop new medicines. We believe tools like Cadence for electrical engineering and Photoshop for graphic design fundamentally changed how experts work by making complex work available on a computer. Molecular engineering deserves software of that caliber, and this category is yours to invent.

  • Work directly with scientists and model researchers to understand how they experiment and make decisions, then turn that understanding into software for working with models and agents.
  • Invent the core concepts and interactions for molecular design on a computer.
  • Prototype and ship these interfaces and tools, owning the work from early design through production code.

About you

We look for exceptional design taste, the engineering ability to prototype and ship, and a track record of distilling complex domains into simple products. You can get to the heart of a difficult problem without losing the details that matter.

Familiarity with the scientific domain is a bonus, but not a requirement. We care more about what you’ve built and the design decisions behind it.

Chai Discovery's standard text

We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect & promote a culture of high velocity and ownership. We compensate our team accordingly.

What this role asks for

55% of this description is written for the role. The rest is Chai Discovery's standard text, folded away below.

Read against Chai Discovery's other open postings on this site.

The team: Platform & Products HIRES STEADILY

This role is one of 5 open in Platform & Products. 2 were posted in the last 30 days and the oldest in June: a team that hires all year rather than one being built.

OTHER ROLES ON THIS TEAM

From the team and dates on Chai Discovery's own job board.

Salary context

43 other open postings titled Design Engineer state a salary: median USD 160,000 to USD 230,000 a year.

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