Senior Software Engineer, ML Platform
- Salary
- $205,000 - $275,000 annually
- Level
- Senior
Not stated in the posting: work type, visa.
Open. First seen 2 October 2026.
About the role
About Xaira Therapeutics
Xaira Therapeutics's standard text
Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification.
Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London.
About the Role
We are seeking a Senior Software Engineer to join our Platform team to design, build, and deploy the AI infrastructure that powers our world-class research team. In this role, you’ll collaborate closely with AI Scientists and other engineers to enable the effective use of thousands of GPUs for training and inferencing cutting-edge biological foundation models.
This role spans a range of problems and skillsets, ranging from MLOps of cutting-edge GPU clusters, to backend engineering of control plane APIs. Our ideal candidate has an opinion about slurm or kubernetes for model training, cares about maximizing bandwidth from the storage subsystems to the GPU, and can build the API paved path for submitting training jobs that are able to dispatch to multiple clusters.
What You Will Do
- Develop and improve our model training system, responsible for dispatching distributed training jobs to clusters across multiple clouds.
- Deploy storage subsystems that improve dataset management and throughput for training datasets.
- Build evaluation infrastructure that enables easy execution and tracking.
- Build base tooling for integrating model training with other internal infrastructure, such as telemetry, experiment tracking, and checkpointing.
- Prior experience with biology is not required - we will teach what you need to know. You’ll get to go in the lab, and for our ideal candidate, this should be a perk, not a chore!
Preferred Skills and Qualifications
- Degree in Computer Science, Machine Learning, Computational Biology, or a related field.
- 5+ years of industry experience building and deploying ML systems in production environments
- Experience leading technical projects and driving cross-functional execution.
- Strong programming skills in Python.
- Experience with infrastructure/ops tools such as Terraform, Ansible.
- Experience with deep learning frameworks such as Torch, Jax.
- Solid understanding of machine learning
- Experience with the infrastructure needs of large-scale model training.
- Strong problem-solving skills and ability to work in a collaborative, multidisciplinary environment.
Compensation
We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants. We offer a competitive package that includes base salary, bonus, and equity.
The base pay range for this position is expected to be $205,000 - $275,000 annually with a total cash compensation up to $235,000 - $325,000; however, the compensation offered may vary depending on the market, job-related knowledge, skills and capabilities, and experience.
Xaira Therapeutics's standard text
Xaira Therapeutics an equal-opportunity employer. We believe that our strength is in our differences. Our goal to build a diverse and inclusive team began on day one, and it will never end.
TO ALL RECRUITMENT AGENCIES: Xaira Therapeutics does not accept agency resumes. Please do not forward resumes to our jobs alias or employees. Xaira Therapeutics is not responsible for any fees related to unsolicited resumes.
What this role asks for
Particular to this role
Ansible · Kubernetes · MLOps · Terraform
Rare in Xaira Therapeutics's other 16 open postings.
Standard for data science / ML roles
Machine Learning · Python
Common in data science / ML postings at any company.
In most of Xaira Therapeutics's ads
Generative AI
Named in most of its open postings, whatever the role.
72% of this description is written for the role. The rest is Xaira Therapeutics's standard text, folded away below.
Compared with Xaira Therapeutics's other open jobs.
The team: Computational Protein Design
This role is one of 7 open in Computational Protein Design.
WHAT THE TEAM WORKS WITH, ACROSS ITS POSTINGS
Generative AI (7 of 7), Machine Learning (5 of 7), Deep Learning (4 of 7), Python (3 of 7), PyTorch (2 of 7)
OTHER ROLES ON THIS TEAM
- Lab Software Engineer posted Sep 3
- AI Scientist Intern, Computational Protein Design posted Aug 28
- AI in Residence, Computational Protein Design posted Aug 20
- Senior Software Engineer, X-Scientist posted Jun 11
- AI Scientist, Computational Protein Design posted Oct 24
- Senior/ Staff AI Research Engineer posted Oct 24
From the team and dates on Xaira Therapeutics's own job board.
See Software Engineer salaries in the United States →
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