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Watershed Informatics

Site Reliability Engineer

Cambridge, MA
Level
Mid

Not stated in the posting: salary, work type, visa.

Open. First seen 3 October 2026.

About the role

About Watershed

Our vision is to become the leading biocomputing platform. The future of biology is in big data analysis, and we are on a mission to accelerate digital drug discovery with the Watershed platform. Watershed enables scientists to conduct all essential analysis — from lab data to plot — with a single software platform.

We have attracted some of the best bioinformatics, engineering, and commercial talent, and we are growing! Join a team that’s intellectually curious with a bias for action, headquartered in Cambridge, Massachusetts, composed of people who have come together to enable outcomes while empowering the research of all those committed to changing lives — all while bringing transformational change to a $40 billion industry.

Role

Linux Systems Engineers at Watershed engineer infrastructure to meet the high-performance computing needs of modern biology. Designing systems that keep pace with the explosive growth in the kinds and size of biological data, you will work in a highly-customized bare metal environment where our biocomputing platform and analyses run at scale. You will be tasked with engineering a new cloud experience while enabling our technology evolution in a disciplined way.

Responsibilities

  • Build, manage, and deploy a large fleet of Linux servers
  • Research new technologies and solutions, implement them or build better
  • Be the connection between hardware and software
  • Monitor system performance and manage capacity.
  • Fix and analyze technical incidents, solve ad hoc technical problems.

Qualifications

  • Experience composing infrastructure-as-code for a modern environment
  • Demonstrate a software developer mindset, building tools when necessary
  • Knowledge of virtualization, networking, and Linux Kernel internals
  • Ability to clearly communicate your thoughts, ask the right questions, and defend your views
  • Responsibility and ownership over your domain.

The team: Engineering

This role is one of 6 open in Engineering.

WHAT THE TEAM WORKS WITH, ACROSS ITS POSTINGS

Linux (4 of 6), Python (3 of 6), JavaScript (2 of 6), Unix (2 of 6)

OTHER ROLES ON THIS TEAM

From the team and dates on Watershed Informatics's own job board.

Salary context

48 other open postings titled Site Reliability Engineer state a salary: median USD 127,500 to USD 195,000 a year.

See Site Reliability Engineer salaries in the United States →

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