Senior HPC & GPU Infrastructure Engineer
- Salary
- $150K - $220K
- Level
- Senior
- Work type
- On-site · San Francisco
Not stated in the posting: visa.
Open. First seen 6 November 2026.
About the role
Sciforium is an AI infrastructure company developing next-generation multimodal AI models and a proprietary, high-efficiency serving platform. Backed by multi-million-dollar funding and direct sponsorship from AMD with hands-on support from AMD engineers the team is scaling rapidly to build the full stack powering frontier AI models and real-time applications.
About the role
We are seeking a Senior HPC & GPU Infrastructure Engineer to take full ownership of the health, reliability, and performance of our GPU compute cluster. You will be the primary custodian of our high-density accelerator environment and the linchpin between hardware operations, distributed systems, and machine learning workflows. This role spans everything from hands-on Linux systems engineering and GPU driver bring-up to maintaining the ML software stack (CUDA/ROCm, PyTorch, JAX, vLLM).
If you love squeezing every bit of performance out of hardware, enjoy debugging GPUs at scale, and want to build world-class AI infrastructure, this role is for you.
What you'll do
1. System Health & Reliability (SRE)
- On-Call Response: Act as the primary responder for system outages, GPU failures, node crashes, and cluster-wide incidents. Minimize downtime by resolving issues rapidly.
- Cluster Monitoring: Implement and maintain monitoring for GPU health, thermal behavior, PCIe/NVLink topology issues, memory errors, and overall system load.
- Vendor Liaison: Coordinate with data center staff, hardware vendors, and on-site technicians for repairs, RMA processing, and physical maintenance of the cluster.
2. Linux & Network Administration
- OS Management: Install, patch, and maintain Linux distributions (Ubuntu / CentOS / RHEL). Ensure consistent configuration, kernel tuning, and automation for large node fleets.
- Security & Access Controls: Configure VPNs, iptables/firewalls, SSH hardening, and network routing to secure our computer infrastructure.
- Identity & Storage Management: Manage LDAP/FreeIPA/AD for user identity, and administer distributed file systems such as NFS, GPFS, or Lustre.
3. GPU & ML Stack Engineering
- Deployment & Bring-Up: Lead deployment of new GPU nodes, including BIOS configuration, NUMA tuning, GPU topology validation, and cluster integration.
- Driver & Kernel Management: Build and optimize kernel modules, maintain GPU drivers and runtime stacks for both NVIDIA (CUDA) and AMD (ROCm).
- Software Stack Maintenance: Maintain and optimize ML frameworks and libraries PyTorch, JAX, CUDA toolkit, cuDNN, ROCm, NCCL, and supporting runtime systems.
- Advanced Debugging: Troubleshoot complex interactions involving GPUs, compilers, ML frameworks, and distributed training runtimes (e.g., vLLM compilation failures, CUDA memory leaks, ROCm kernel crashes).
Ideal candidate profile
- 5+ years of experience in HPC, GPU cluster operations, Linux systems engineering, or similar roles.
- Bachelor’s or Master’s degree in Computer Science, Computer Engineering, Electrical Engineering, or a related technical field.
- Strong expertise with NVIDIA (H100/B200) or AMD (MI325x/MI355x) GPUs, including driver and kernel-level debugging.
- Deep understanding of Linux internals, kernel modules, hardware bring-up, and systems performance tuning.
- Experience with network security, including VPNs, iptables/firewalld, SSH, and identity management (LDAP/FreeIPA/AD).
- Proficiency in Bash and Python for scripting, automation, and workflow tooling.
- Familiarity with ML software stacks: CUDA toolkit, cuDNN, NCCL, ROCm, JAX/PyTorch runtime behavior.
- Deep debugging experience with NVLink/NVSwitch fabrics and RDMA networking.
Nice-to-have
- Experience with job schedulers such as Slurm, Kubernetes, or Run:AI.
- Exposure to vLLM, model serving optimizations, or inference systems.
- Hands-on experience with configuration management tools (Ansible, SaltStack, Terraform).
- Previous experience supporting ML research teams in a startup or research-heavy environment.
Benefits include
- Medical, dental, and vision insurance
- 401k plan
- Daily lunch, snacks, and beverages
- Flexible time off
- Competitive salary and equity
Sciforium's standard text
Equal opportunity
Sciforium is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.
What this role asks for
Particular to this role
Linux Kernel
Rare in Sciforium's other 23 open postings.
Standard for DevOps / SRE / cloud roles
Kubernetes · Linux · Terraform
Common in DevOps / SRE / cloud postings at any company.
In most of Sciforium's ads
Machine Learning · Python
Named in most of its open postings, whatever the role.
95% of this description is written for the role. The rest is Sciforium's standard text, folded away below.
Compared with Sciforium's other open jobs.
The team: Engineering HIRES STEADILY
This role is one of 24 open in Engineering. 2 were posted in the last 30 days and the oldest in November: a team that hires all year rather than one being built.
WHAT THE TEAM WORKS WITH, ACROSS ITS POSTINGS
Python (20 of 24), LLM (16 of 24), Machine Learning (16 of 24), CUDA (12 of 24), C++ (10 of 24), Kubernetes (10 of 24), PyTorch (10 of 24)
OTHER ROLES ON THIS TEAM
- GPU Kernel Engineer posted Oct 26
- GPU Kernel Engineer posted Oct 26
- Senior HPC & GPU Infrastructure Engineer posted Oct 6
- Foundation Model Data Engineer posted Sep 28
- Foundation Model Data Engineer posted Sep 28
- Pre-training Research Engineer posted Aug 31
- Pre-training Research Engineer posted Aug 31
- Research Engineer - Model Evaluation & MLOps posted Aug 31
- Research Engineer - Model Evaluation & MLOps posted Aug 31
- Distributed Training and Inference Engineer posted Aug 24
- Distributed Training and Inference Engineer posted Aug 24
- Lead Software Engineer, Model Serving Platform posted Aug 17
- Lead Software Engineer, Model Serving Platform posted Aug 17
- Software Engineer, Fullstack posted Aug 7
- Software Engineer, Fullstack posted Aug 7
- GPU Cluster Engineer, Networking posted Aug 6
- GPU Cluster Engineer, Networking posted Aug 6
- GPU Cluster Engineer, Systems & Platform posted Aug 6
- GPU Cluster Engineer, Systems & Platform posted Aug 6
- GPU Cluster Engineer, Hardware Operations posted Jul 8
- GPU Cluster Engineer, Hardware Operations posted Jul 8
- Senior AI Serving Engineer, Backend posted Nov 15
- Senior AI Serving Engineer, Backend posted Nov 15
From the team and dates on Sciforium's own job board.
Other openings for this role
2 open postings for this role in San Francisco, CA, first posted 6 October 2026. The company is likely hiring for more than one position. None has been taken down and posted again.
- 6 November 2026 – open (this posting)
- 6 October 2026 – open
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