Lead Platform Engineer
- Salary
- $205,000 - $235,000 annually
- Level
- Lead
- Work type
- On-site · South San Francisco
- Visa
- Sponsors visas
Open. First seen 2 November 2026.
About the role
About the Role
Lead the compute, data, AI, and security infrastructure behind a biotechnology sequencing operation. This hands-on technical leadership role connects laboratory systems with reliable cloud platforms and data workflows that support scientific work.
What You'll Do
- Own services that orchestrate laboratory devices, including robots, sequencers, and on-premises Linux servers, along with the data ingestion pipeline.
- Build cloud infrastructure and data pipelines to store, process, and deliver large volumes of sequencing data.
- Design reliable systems for orchestrating large-scale bioinformatics workloads, including queues, workflow orchestration, and scheduling.
- Develop AI infrastructure and internal tools for operational quality monitoring, logistics coordination, and adaptive bioinformatics analysis.
- Lead cross-functional projects from problem definition through production, connecting architectural decisions to business impact.
- Contribute directly to implementation while mentoring engineers and communicating across scientific and engineering teams.
What We're Looking For
- At least 5 years of experience in platform, backend, or infrastructure engineering, including meaningful experience at a startup as it scaled.
- Strong AWS orchestration experience with ECS, Batch, and Step Functions, plus Python backend development using FastAPI or Django.
- Experience designing and shipping reliable distributed systems, including queues, orchestration, and state machines.
- Linux server administration experience and familiarity with distributed task queues such as Celery or SQS.
- Experience leading cross-functional projects and mentoring engineers on a small team, with a substantial hands-on individual contributor focus.
- Current familiarity with AI tooling; experience building LLM or agent systems, including tools, evaluation, safety, permissions, prompts, and workflows, is valuable.
- A technical degree or equivalent background, and curiosity about biotechnology, science, and scientific applications.
Compensation & Benefits
Base salary is $205,000 to $235,000 USD annually. Visa sponsorship is available.
Location
Hybrid in South San Francisco, California, United States.
What this role asks for
Particular to this role
Celery · Django · FastAPI
Rare in True Talent Solutions Partners's other 124 open postings.
Standard for DevOps / SRE / cloud roles
AWS · Linux · Python
Common in DevOps / SRE / cloud postings at any company.
Compared with True Talent Solutions Partners's other open jobs.
The team: Client Roles
This role is one of 125 open in Client Roles. 125 were posted in the last 30 days, including 7 lead roles: the team is hiring the people who run it too.
WHAT THE TEAM WORKS WITH, ACROSS ITS POSTINGS
Python (64 of 125), TypeScript (45 of 125), LLM (44 of 125), React (41 of 125), JavaScript (28 of 125), AWS (24 of 125), Machine Learning (24 of 125)
OTHER ROLES ON THIS TEAM
- Founding AI Agent Engineer posted Nov 2
- Senior Forward Deployed Engineer, Operate posted Nov 2
- Engineering Lead posted Nov 2
- Robotics Software Engineer posted Nov 2
- Product Manager, AI Platform posted Nov 2
- Staff Software Engineer, Infrastructure posted Nov 2
- Senior Software Engineer, Autonomous Systems posted Nov 2
- Agent Deployment Engineer posted Nov 2
- Engineering Manager, Agents posted Nov 2
- Founding Fullstack Engineer posted Nov 2
- Founding Product Designer posted Nov 2
- Founding PLM Solutions Engineer posted Nov 2
- Forward Deployed Engineer posted Nov 2
- Software Engineer posted Nov 2
- Design Engineer posted Nov 2
- Research Crawling Engineer posted Nov 2
- Senior/Staff Software Engineer posted Nov 2
- Software Engineer, AI Agents posted Nov 2
- Senior Full-Stack Engineer posted Nov 2
- Full-Stack Engineer, AI Agents posted Nov 2
- Senior Power Electronics Engineer posted Nov 2
- Software Engineer, Marketplace posted Nov 2
- Engineering Manager posted Nov 2
- Senior AI/ML Engineer posted Nov 2
- Mechanical Engineer posted Nov 2
- Computer Vision ML / Research Engineer posted Nov 2
- Senior Software Engineer posted Nov 2
- Senior Full Stack Engineer posted Nov 2
- Member of Technical Staff, ML Systems posted Nov 2
- AI-Native Electrical Engineer posted Nov 2
- Mid/Senior Full Stack AI Engineer posted Nov 2
- Forward Deployed Product Manager posted Nov 2
- Director of Engineering posted Nov 2
- Founding Senior Engineer posted Nov 2
- Product Lead posted Nov 2
- Forward Deployed Engineer posted Nov 2
- Senior Backend Software Engineer posted Nov 2
- Staff Product Manager posted Nov 2
- Founding Product Designer posted Nov 2
- Member of Technical Staff, Applied Researcher posted Nov 2
- Senior Security Engineer posted Nov 2
- Senior Solutions Engineer, Digital Native and Mid-Market posted Nov 2
- Product Engineer posted Nov 2
- Senior/Staff Product Engineer, Applied AI posted Nov 2
- Software Engineer, C++ Systems posted Nov 2
- Senior Software Engineer posted Nov 2
- Member of Technical Staff, AI Agents posted Nov 2
- Lead Software Engineer, Platform posted Nov 2
- Technical Product Manager posted Nov 2
- Senior Forward Deployed Engineer posted Nov 2
- Senior Control Electronics Engineer posted Nov 1
- Research Engineer, Evals posted Nov 1
- Software Engineer posted Nov 1
- Founding Product Engineer posted Nov 1
- Fullstack Software Engineer posted Nov 1
- Frontend Engineer posted Nov 1
- Founding Forward Deployed Engineer posted Nov 1
- Founding AI Engineer posted Nov 1
- Founding ML Research Engineer posted Nov 1
- Senior Platform Engineer posted Nov 1
- Member of Technical Staff, Compiler posted Nov 1
- Forward Deployed Engineer posted Nov 1
- Founding Engineer posted Nov 1
- Product Engineer, Mid-Senior posted Nov 1
- AI Scheduler posted Nov 1
- Lead Product Engineer posted Nov 1
- Product Manager, Supply Chain posted Nov 1
- Founding Full-Stack Engineer posted Nov 1
- Founding Forward Deployed Engineer posted Nov 1
- Founding Product Designer posted Nov 1
- Product Manager, Product Growth posted Nov 1
- Software Engineer, iOS posted Nov 1
- Senior Full Stack Software Engineer posted Nov 1
- Electrical & Computer Engineer posted Nov 1
- Founding Backend Software Engineer posted Nov 1
- Engineering Manager posted Nov 1
- Member of Technical Staff posted Nov 1
- Technical Recruiter posted Nov 1
- Product Manager, AI Education posted Nov 1
- Agent Deployment Engineer posted Nov 1
- Full Stack Engineer posted Nov 1
- Forward Deployed Engineer posted Nov 1
- Brand & Identity / Presentation Designer posted Nov 1
- Senior Full-Stack Software Engineer posted Nov 1
- Founding Engineer posted Nov 1
- Full-Stack Product Engineer posted Nov 1
- Senior ML / AI Engineer posted Nov 1
- Full-Stack Engineer, Agent Evaluation & Reliability posted Nov 1
- Senior LATAM Brazil QA Engineer posted Nov 1
- Senior Full-Stack Engineer posted Nov 1
- Director of Engineering posted Nov 1
- GTM Engineer posted Nov 1
- Forward Deployed Engineer posted Nov 1
- Senior / Staff Product Engineer posted Nov 1
- Member of Technical Staff posted Nov 1
- Senior Analog/Mixed Signal Engineer posted Nov 1
- Forward Deployed Product Manager posted Nov 1
- Software Engineer, Distributed Systems (Core) posted Nov 1
- Founding Engineer posted Nov 1
- Member of Technical Staff posted Nov 1
- Product Engineer, Scrape posted Nov 1
- Lead Platform Engineer posted Nov 1
- Solutions Engineer posted Nov 1
- Principal Software Engineer, Perception posted Nov 1
- Backend Infrastructure Engineer, Anti-Bot posted Nov 1
- Principal Analog/Mixed-Signal Engineer posted Oct 31
- Senior Member of Technical Staff, Platform posted Oct 31
- Robotics Infrastructure Engineer posted Oct 31
- Staff Product Manager, AI posted Oct 31
- Member of Technical Staff, Research Engineering posted Oct 31
- Founding Product Engineer posted Oct 31
- Head of RF Engineering posted Oct 31
- Software Engineer, Security posted Oct 31
- Senior Software Engineer, Customer Studio Backend posted Oct 31
- Technical Product Manager posted Oct 31
- Founding Software Engineer posted Oct 31
- Electrical Engineer posted Oct 31
- Founding Engineer posted Oct 30
- Data Engineer, Data Product posted Oct 30
- Senior Product Manager, Staffing and AI Agents posted Oct 30
- Founding Product Engineer posted Oct 30
- Software Engineer posted Oct 30
- Senior Software Engineer, Design posted Oct 30
- Member of Technical Staff, Full Stack posted Oct 30
From the team and dates on True Talent Solutions Partners's own job board.
Posting history
Reposted once since 28 October 2026: a posting for this role in South San Francisco was taken down and the role was posted again.
- 2 November 2026 – open (this posting)
- 28 October 2026 – closed 1 November 2026
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