Senior Software Engineer, Core Systems
- Salary
- $215,000 - $275,000 annually
- Level
- Senior
- Work type
- On-site · San Francisco
- Visa
- Sponsors visas
Open. First seen 5 November 2026.
About the role
About the Role
Join a small engineering team building backend infrastructure for a healthcare technology platform supporting radiology workflows and AI-assisted diagnosis. You will own foundational systems across data ingestion, storage, and distributed model inference.
What You'll Do
- Design, build, and operate backend infrastructure for data ingestion, warehousing, and distributed model inference on AWS.
- Own reliability, observability, debugging, and capacity planning across the stack.
- Build CI/CD and deployment automation to help the team ship safely and efficiently.
- Design systems that handle protected health information with encryption, access controls, and audit logging.
- Work with the machine learning team on infrastructure and model inference pipelines as priorities require.
What We're Looking For
- At least 5 years of experience in backend engineering, data infrastructure, or distributed systems.
- Production experience building and operating large-scale distributed systems on AWS or a comparable cloud platform.
- Proficiency in Python, Go, or Java, with strong hands-on backend engineering skills.
- Experience with data pipelines, ETL, warehouses or data lakes, schema evolution, and deployment automation.
- Track record leading multi-quarter technical initiatives across systems or teams, along with experience on a small, fast-moving team.
- Ability to troubleshoot complex distributed systems and weigh performance, cost, security, and maintainability tradeoffs.
- Exposure to machine learning infrastructure or model inference pipelines, HIPAA-compliant system design, and TypeScript or React is valuable.
- A STEM degree or strong computer science fundamentals.
Compensation & Benefits
Base salary: $215,000 to $275,000 annually. Visa sponsorship is available.
Location
On-site in San Francisco, California, United States.
What this role asks for
Particular to this role
CI/CD · ETL · Golang · Java
Rare in True Talent Solutions Partners's other 125 open postings.
Standard for software engineering roles
Python
Common in software engineering postings at any company.
Compared with True Talent Solutions Partners's other open jobs.
The team: Client Roles
This role is one of 126 open in Client Roles. 126 were posted in the last 30 days, including 6 lead roles: the team is hiring the people who run it too.
WHAT THE TEAM WORKS WITH, ACROSS ITS POSTINGS
Python (73 of 126), TypeScript (47 of 126), LLM (46 of 126), React (43 of 126), Machine Learning (37 of 126), AWS (32 of 126), JavaScript (27 of 126)
OTHER ROLES ON THIS TEAM
- Product Manager, Product Growth posted Nov 5
- Founding Backend Software Engineer posted Nov 5
- Electrical & Computer Engineer posted Nov 5
- Software Engineer, iOS posted Nov 5
- Founding AI Agent Engineer posted Nov 5
- Staff Software Engineer, Infrastructure posted Nov 5
- Data Engineer, Data Product posted Nov 5
- Product Manager, AI Agents posted Nov 5
- Founding Product Engineer posted Nov 5
- Software Engineer posted Nov 5
- Senior Software Engineer, Design posted Nov 5
- Member of Technical Staff, Full Stack posted Nov 5
- Mechanical Design Engineer posted Nov 5
- Senior/Staff Software Engineer posted Nov 5
- Forward Deployed Engineer, Infrastructure posted Nov 5
- Founding Member of Technical Staff, Markets posted Nov 5
- Founding Full-Stack Engineer posted Nov 5
- Software Engineer posted Nov 5
- Founding Research Engineer, Robot Learning posted Nov 5
- Machine Learning Infrastructure Engineer posted Nov 5
- Senior Platform Security Engineer posted Nov 5
- Software Engineer, Mid-Level to Staff+ posted Nov 5
- Senior Security Engineer posted Nov 5
- Head of Software Architecture, Embodied AI Platform posted Nov 5
- AI Solutions Consultant posted Nov 5
- Agent Deployment Engineer posted Nov 5
- Lead AI Engineer posted Nov 5
- Member of Technical Staff, Applied ML posted Nov 5
- Founding Engineer posted Nov 5
- Product Engineer posted Nov 5
- Senior Full Stack Engineer posted Nov 5
- Full Stack Engineer posted Nov 5
- Mid/Senior Full Stack AI Engineer posted Nov 5
- Member of Technical Staff posted Nov 5
- Senior Backend Software Engineer posted Nov 5
- Forward Deployed Product Manager posted Nov 5
- Senior Software Engineer, Autonomous Systems (C2/Backend/Service) posted Nov 5
- Senior Solutions Engineer, Digital Native and Mid-Market posted Nov 5
- Engineering Lead posted Nov 5
- Staff Product Manager posted Nov 5
- Director of Engineering, Product posted Nov 5
- Founding Product Designer posted Nov 5
- Product Engineer posted Nov 5
- Founding Engineer posted Nov 5
- Founding Forward Deployed Engineer posted Nov 5
- Member of Technical Staff, ML Systems posted Nov 5
- Technical Product Manager posted Nov 5
- Research Engineer, Evals posted Nov 5
- Frontend Engineer posted Nov 5
- AI Scheduler posted Nov 5
- Product Manager, Supply Chain posted Nov 5
- Forward Deployed Engineer posted Nov 5
- Member of Technical Staff, Compiler posted Nov 5
- Founding ML Research Engineer posted Nov 5
- Founding AI Engineer posted Nov 5
- Founding Senior Engineer posted Nov 5
- Robotics Software Engineer posted Nov 5
- Product Engineer, Mid-Senior posted Nov 5
- Senior Forward Deployed Engineer, Operate posted Nov 5
- Founding Full-Stack Engineer posted Nov 4
- Lead Product Engineer posted Nov 4
- Agent Product Engineer posted Nov 4
- Forward Deployed Engineer posted Nov 4
- Product Engineer, AI posted Nov 4
- Sales Engineer posted Nov 4
- Forward Deployed Engineer posted Nov 4
- Founding Engineer, Applied AI posted Nov 4
- Founding Forward Deployed Engineer posted Nov 4
- Machine Learning Engineer posted Nov 4
- Forward Deployed Engineer posted Nov 4
- Senior Mechanical Engineer posted Nov 4
- Infrastructure Engineer posted Nov 4
- Solutions Engineer posted Nov 4
- Principal Software Engineer, Perception posted Nov 4
- Senior Forward Deployed Engineer posted Nov 4
- Member of Technical Staff, Senior posted Nov 4
- Founding Product Engineer posted Nov 4
- Software Engineer, C++ Systems posted Nov 4
- Senior Platform Engineer posted Nov 3
- Founding Forward Deployed Engineer posted Nov 3
- Founding Product Engineer posted Nov 3
- Senior Product Manager posted Nov 3
- Senior Member of Technical Staff, Agent Platform posted Nov 3
- Software Engineer, Infrastructure posted Nov 3
- Forward Deployed Software Engineer, Tactical Edge posted Nov 3
- Software Engineer, RL Environments posted Nov 3
- Founding Backend & Infrastructure Engineer posted Nov 3
- Founding Reinforcement Learning Engineer posted Nov 3
- Senior Quantitative Developer posted Nov 3
- Founding Forward Deployed Engineer posted Nov 3
- Senior Engineering Manager posted Nov 3
- Full-Stack Software Engineer posted Nov 3
- Founding Engineer, Forward Deployed posted Nov 3
- Full Stack Engineer posted Nov 3
- Senior Data & Machine Learning Engineer posted Nov 3
- AI-Native Electrical Engineer posted Nov 3
- Senior/Staff Full Stack Engineer posted Nov 3
- Founding Engineer posted Nov 3
- Product Engineer posted Nov 3
- Lead Platform Engineer posted Nov 3
- Full-Stack Engineer, Agent Evaluation & Reliability posted Nov 3
- Senior/Staff Product Engineer, Applied AI posted Nov 3
- Senior Control Electronics Engineer posted Nov 3
- Lead Software Engineer, Platform posted Nov 3
- Fullstack Software Engineer posted Nov 3
- Product Manager, AI Platform posted Nov 2
- Agent Deployment Engineer posted Nov 2
- Engineering Manager, Agents posted Nov 2
- Founding Fullstack Engineer posted Nov 2
- Lead Platform Engineer posted Nov 2
- Founding Product Designer posted Nov 2
- Founding PLM Solutions Engineer posted Nov 2
- Forward Deployed Engineer posted Nov 2
- Software Engineer posted Nov 2
- Research Crawling Engineer posted Nov 2
- Senior/Staff Software Engineer posted Nov 2
- Software Engineer, AI Agents posted Nov 2
- Senior Full-Stack Engineer posted Nov 2
- Senior Power Electronics Engineer posted Nov 2
- Software Engineer, Marketplace posted Nov 2
- Engineering Manager posted Nov 2
- Senior AI/ML Engineer posted Nov 2
- Mechanical Engineer posted Nov 2
- Computer Vision ML / Research Engineer posted Nov 2
- Senior Software Engineer posted Nov 2
From the team and dates on True Talent Solutions Partners's own job board.
Posting history
Reposted 3 times since 25 October 2026: a posting for this role in San Francisco was taken down and the role was posted again.
- 5 November 2026 – open (this posting)
- 29 October 2026 – closed 2 November 2026
- 28 October 2026 – closed 29 October 2026
- 25 October 2026 – closed 26 October 2026
See Software Engineer salaries in San Francisco →
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